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What is THCp?

THCp (Tetrahydrocannabiphorol) is a naturally occurring cannabinoid known for its significantly higher potency compared to regular THC. Its unique structure allows for a stronger interaction with the endocannabinoid system, providing more intense and prolonged effects.

What is Tetrahydrocannabiphorol?

Here's what to know 

If you're curious about the latest developments in the world of cannabinoids, you may have heard whispers about a new compound called THC-P. This rare phytocannabinoid, discovered in 2019, has been making waves in the cannabis community due to its unique chemical structure and potentially powerful effects.

THC-P, short for tetrahydrocannabiphorol, is a naturally occurring phytocannabinoid found in trace amounts in the cannabis plant. It was first isolated and identified by a team of Italian researchers in 2019.

THC-P's chemical structure is similar to that of delta-9 THC, the primary psychoactive compound in cannabis, but with one notable difference: THC-P has a seven-term alkyl side chain, while delta-9 THC has a five-term alkyl side chain.


This longer side chain gives THC-P a significantly stronger binding affinity to the CB1 receptors in the body's endocannabinoid system, which are primarily responsible for the psychoactive effects of cannabinoids.

In fact, studies suggest that THC-P may be up to 33 times more potent than delta-9 THC in its ability to bind to CB1 receptors and produce psychoactive effects.

However, despite its potency, THC-P is found only in trace amounts in cannabis plants. This scarcity makes it challenging to extract and study, which is why it took until 2019 for researchers to isolate and identify this unique phytocannabinoid successfully.

As more research is conducted, we may learn more about THC-P's prevalence in different cannabis strains and how it contributes to the plant's overall effects.

How is THC-P Different from Other Cannabinoids?

While THC-P shares some similarities with other cannabinoids, its unique chemical structure sets it apart and influences its effects on the body and mind.

THC-P vs. Delta-9 THC

  • Chemical Structure: THC-P has a seven-term alkyl side chain, while delta-9 THC has a five-term alkyl side chain. This difference in structure gives THC-P a stronger binding affinity to CB1 receptors.

  • Potency: THC-P is believed to be up to 33 times more potent than delta-9 THC in its ability to produce psychoactive effects.

  • Prevalence: Delta-9 THC is the most abundant psychoactive cannabinoid in cannabis, while THC-P is found only in trace amounts.

THC-P vs. Delta-8 THC

  • Psychoactive Effects: Both THC-P and delta-8 THC produce psychoactive effects, but THC-P is significantly more potent due to its stronger binding affinity to CB1 receptors.

  • Legal Status: Delta-8 THC is often synthesized from CBD and falls into a legal gray area, while THC-P derived from hemp is currently legal under the 2018 Farm Bill.

  • Availability: Delta-8 THC products have become increasingly popular and widely available, while THC-P products are still relatively rare and new to the market.


  • Effects: THCV is known for its potential appetite-suppressing and energizing effects, while THC-P is associated with potent psychoactive effects and potential therapeutic benefits.

  • Potency: THC-P is significantly more potent than THCV in its ability to bind to CB1 receptors and produce psychoactive effects.

  • Research: THCV has been studied more extensively than THC-P, which was only recently discovered and is still the subject of ongoing research.

Potential Benefits and Effects of THC-P

While research on THC-P is still in its early stages, initial findings and anecdotal reports suggest that this potent phytocannabinoid may offer a range of potential benefits and effects.

Enhanced Pain Relief

One of the most promising potential benefits of THC-P is its ability to provide enhanced pain relief. Its strong binding affinity to CB1 receptors suggests that it may effectively manage chronic pain, inflammation, and other pain-related conditions.

Increased Appetite Stimulation

Like delta-9 THC, THC-P may also have appetite-stimulating effects, which could be beneficial for individuals undergoing chemotherapy, living with HIV/AIDS, or struggling with eating disorders.

Potent Psychoactive Effects

THC-P's potency means it can produce powerful psychoactive effects, even in small doses. This could be appealing to recreational users seeking a more intense experience, but it also highlights the importance of responsible use and careful dosing.

Potential Therapeutic Applications

As research on THC-P continues, scientists may uncover additional therapeutic applications for this potent phytocannabinoid. Its strong binding affinity to CB1 receptors suggests that it could be useful in treating a range of conditions, from chronic pain and inflammation to anxiety and sleep disorders.

How Does THC-P Work in the Body?


THC-P, like other cannabinoids, interacts with the body's endocannabinoid system (ECS). The ECS is a complex network of receptors, enzymes, and endogenous cannabinoids that plays a crucial role in regulating various physiological processes, including pain, mood, appetite, and sleep.

THC-P binds strongly to the CB1 receptors in the ECS, which are primarily found in the central nervous system and are responsible for the psychoactive effects of cannabinoids. This strong binding affinity is attributed to THC-P's seven-term alkyl side chain, which allows it to fit more snugly into the CB1 receptor and produce more potent effects compared to other cannabinoids with shorter side chains, like delta-9 THC.

When THC-P binds to CB1 receptors, it can trigger a cascade of physiological responses, including altered perception, mood changes, pain relief, and appetite stimulation. The strength and duration of these effects may vary depending on factors such as dosage, individual physiology, and tolerance levels.

Research indicates that THC-P’s potent binding to CB1 receptors can lead to significant psychoactive effects, including enhanced relaxation, euphoria, and potential pain relief. These findings suggest that THC-P could offer substantial therapeutic benefits​.

As research on THC-P progresses, we may gain a deeper understanding of how this unique phytocannabinoid interacts with the ECS and other receptor systems in the body, paving the way for targeted therapeutic applications and personalized cannabis medicine.

Is THC-P Legal?

The legal status of THC-P is still somewhat ambiguous and may vary depending on the source of the cannabinoid and individual state laws.

Under the 2018 Farm Bill, hemp-derived cannabinoids are considered legal at the federal level, as long as they contain less than 0.3% delta-9 THC by dry weight. This means that THC-P derived from hemp plants that meet this criterion could be considered legal under federal law.

However, it's important to note that state laws may differ, and some states may have more restrictive regulations regarding hemp-derived cannabinoids. Additionally, as THC-P is a relatively new discovery, it may not be explicitly addressed in current legislation, leading to potential gray areas.

As research on THC-P continues and its popularity grows, it's likely that federal and state regulations will evolve to provide more clarity on its legal status. It's crucial for individuals to stay informed about the latest laws and regulations in their area and to purchase THC-P products from reputable sources that comply with all relevant legal requirements.

THC-P Safety and Side Effects

As with any potent cannabinoid, THC-P use comes with potential risks and side effects that users should be aware of.

Safety and quality are our top priorities. Our THC-P Distillate undergoes rigorous testing to ensure purity and potency so you can enjoy its powerful effects with confidence. Learn more about our testing process and shop THC-P Distillate.

Potential for Intense Psychoactive Effects

Due to its high binding affinity to CB1 receptors, THC-P can produce powerful psychoactive effects, even in small doses. This potency can be overwhelming for some users, particularly those with a low tolerance or sensitivity to THC. Intense psychoactive effects may include altered perception, impaired coordination, anxiety, paranoia, and increased heart rate.

Importance of Responsible Use and Dosing

Given THC-P's potency, it's crucial for users to approach this cannabinoid with caution and practice responsible use. Starting with a low dose and gradually increasing as needed can help minimize the risk of adverse effects. It's also important to consume THC-P in a safe, comfortable environment and to avoid driving or operating heavy machinery while under its influence.

Limited Research on Long-term Effects

As THC-P is a relatively new discovery, there is limited research on its long-term effects and potential health risks. While initial studies suggest that THC-P may offer therapeutic benefits, more research is needed to fully understand its impact on the body and mind over extended periods of use.

As with any cannabinoid, it's essential to stay informed about the latest scientific findings and to consult with a healthcare professional before incorporating THC-P into a wellness or treatment plan.

How is THC-P Made?

  • Trace Amounts in Cannabis Plants: THC-P is found naturally in cannabis plants, but only in very small quantities. This scarcity makes it challenging to extract and isolate THC-P directly from the plant material.


  • Extraction and Isolation Processes: Due to the trace amounts of THC-P in cannabis, specialized extraction and isolation techniques are required to obtain this rare cannabinoid. These processes often involve advanced chromatography methods and can be time-consuming and costly.

  • Chemical Synthesis and Conversion: Many THC-P products on the market are created through chemical synthesis or the conversion of other cannabinoids. For example, CBD can be converted into delta-9 THC, which can then be further transformed into THC-P through a series of chemical reactions.

  • THC-P Distillate Production: One common form of THC-P used in consumer products is THC-P distillate, a highly concentrated oil that contains high levels of THC-P and other minor cannabinoids. THC-P distillate is produced through a combination of extraction, isolation, and distillation processes.

  • Testing and Quality Control: Given the potency of THC-P and the complexity of its production, thorough testing and quality control measures are essential to ensure the safety and consistency of THC-P products. Reputable manufacturers should provide certificates of analysis (COAs) that verify the cannabinoid content and purity of their products.

The Future of THC-P Research and Applications

As the discovery of THC-P is still relatively recent, there is a growing interest in further exploring its potential benefits, risks, and applications. Ongoing studies aim to deepen our understanding of this potent phytocannabinoid and its role in the future of cannabis medicine.

Ongoing Studies on THC-P's Potential Benefits

Researchers are investigating THC-P's potential therapeutic applications, particularly in areas where high-potency cannabinoids may be beneficial, such as pain management, inflammation, and neurological disorders. As more preclinical and clinical studies are conducted, we may gain a clearer picture of THC-P's efficacy and safety profile.

Possibilities for Targeted Therapies and Products

As our understanding of THC-P grows, there may be opportunities to develop targeted therapies and products that harness its unique properties. For example, THC-P could be used in combination with other cannabinoids and terpenes to create personalized cannabis formulations tailored to specific medical conditions or symptoms.

Importance of responsible innovation in the cannabinoid space

As the cannabis industry continues to evolve and new cannabinoids like THC-P emerge, it's crucial for researchers, manufacturers, and policymakers to prioritize responsible innovation. This includes conducting rigorous scientific studies, ensuring product safety and quality control, and providing clear and accurate information to consumers.

Is THC-P Right for You?

If you are considering THC-P for its unique experiences and benefits, here are a few things you should consider:

  • Consider Individual Tolerance and Sensitivity: Given THC-P's potency, it's essential to consider your individual tolerance and sensitivity to cannabinoids before trying THC-P products. If you are new to cannabis or have a low tolerance, it may be best to start with lower-potency cannabinoids and work your way up gradually.

  • Start with Low Doses and Monitor Effects: When trying THC-P for the first time, it's crucial to start with a low dose and monitor your body's response. This will help you gauge your tolerance and avoid potentially overwhelming psychoactive effects. Be patient and give yourself time to assess the full impact of each dose before increasing.

  • Consult With a Healthcare Professional: If you are considering using THC-P for medical purposes, it's essential to consult with a healthcare professional who is knowledgeable about cannabis medicine. They can help you determine whether THC-P is appropriate for your specific condition and guide you on safe dosing and potential interactions with other medications.

  • Stay Informed About the Latest Research: As research on THC-P continues to evolve, it's essential to stay informed about the latest scientific findings. This includes studies on THC-P's potential benefits, risks, and optimal dosing strategies. By staying up-to-date with the most recent research, you can make informed decisions about whether THC-P is right for you.

Arvida Labs is at the forefront of exploring THC-P's potential, offering high-quality products designed to meet your wellness needs. If you're looking to experience the unique benefits of this potent cannabinoid, our carefully crafted selection can help address your pain points effectively.

Ready to experience the unique benefits of THC-P? Arvida Labs offers high-quality THC-P Distillate products tailored to your needs.

Shop our THC-P Distillate now and embrace the future of cannabinoids today.

Sources Used for this Article:

Disclaimer: The information provided on Arvida Labs website is for educational and entertainment purposes only and should not be considered legal or medical advice. While we strive to ensure that the content is accurate and sourced from reputable academic and research institutions, as well as our own laboratories, it is not a substitute for professional consultation with a healthcare provider or legal expert.


Arvida Labs does not endorse or promote the use of any illegal substances and encourages responsible use of legal cannabinoids. Always consult with a qualified healthcare professional before using any cannabinoid products, especially if you have any pre-existing health conditions or are taking medication.


For the most current and accurate information, please refer to trusted sources and verify local laws and regulations regarding cannabinoids.

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